Topic Code HORIZON-HLTH-2026-01-DISEASE-04 F&T Portal
Call Identifier HORIZON-HLTH-2026-01 Call 01 — single stage (2026)
Instrument HORIZON-RIA Research and Innovation Action
Budget Model Actual Costs Standard MGA
Funding Rate 100% Annex G — RIA = 100%
Page Limit (Part B) 40 pages RIA + actual costs (Annex A)
Evaluation Thresholds 4 / 4 / 4 · cum. 12 Non-standard — topic override
Expected Projects 5 €9–11M per project (WP stated)
Destination Tackling diseases and reducing disease burden WP Part 4
Cluster / Pillar Cluster 1 / Pillar II Health
China Eligibility Excluded ⚠ Destination excludes RIA/IA
Special Conditions Portfolio by virus ⚠ Balanced across targeted viruses
Verify: Open this topic on the F&T Portal →  ·  Sources: General Annexes 2026-2027, WP Part 4
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Chinese entities are excluded from RIA actions under this destination. Legal entities established in China are not eligible to participate in Research and Innovation Actions (RIAs) falling under Destination ‘Tackling diseases and reducing disease burden’.
This topic uses non-standard evaluation thresholds: 4 (Excellence) / 4 (Impact) / 4 (Implementation), cumulative 12. Standard thresholds are 3/3/3 cumulative 10.
Portfolio approach: Grants will be awarded to ensure balanced coverage across the targeted viruses (Junin, Lassa, Andes, Hantaan, Sin Nombre, Hendra, Enterovirus D68, Venezuelan equine encephalitis virus), not solely by ranking.
US entities eligible: In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America are eligible to receive Union funding under this topic.
Copernicus/Galileo: If the project uses satellite-based earth observation, positioning, navigation and/or related timing data, beneficiaries must make use of Copernicus and/or Galileo/EGNOS.
Mandatory annex: Proposals under this topic are expected to include clinical studies. Applicants should provide details in the dedicated annex using the template provided in the submission system.

Expected Outcomes

  1. The scientific and clinical communities have a better understanding of and access to experimental vaccines for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation, including better understanding of biological sex and social determinants that influence immune response, vaccine efficacy, safety, and uptake.
  2. Candidate vaccines are available for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic.

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